I don't understand why it could drastically increase the price of a Macbook. I can buy a ThinkPad or a Dell Latitude/Precision with a Sierra Wireless 4G M.2 card for only an extra $2-300, basically the price of the card if you were to buy it separately. Older generations of ThinkPads could also have a 4G M.2 card easily added after purchase because the antennas were built-in from the factory (did this with my X260).

I suppose (guessing) if this was a SoC and there were no standard M.2 slots, then I guess I could see why Qualcomm would want some extra royalties in that case.