I use vim, so esc is one of the most important keys. But I use esc in most apps very frequently. I don’t use Caps Lock at all.
I edit my sources and remote configs exclusively in vim-likes since ~2004 (full time sw dev) and never experienced such issues. From my experience, typing or clicking speed requirement rarely exceeds that of thinking on your program. I hit esc often, but not too often, and it is not too far.
I’m not against caps->esc mapping in general, but for me this would have little to no value plus non-standard layout, which is minus, since I’m not office-only guy.
What is a function in your programs deserve such a prominent position??
In my case as an emacs user bloq mayus, get's remaped to CTRL.
Vin users need ESC.