Not necessarily, a cargo container sized unit would have a limited quantity of fissile material making it more readily dealt with by proper authorities. Given newer self-shutdown models that don’t go critical or meltdown tons of highly reactive material on failure removes issues similar to Fukushima where melted nuclear material erodes containment and embeds into the ground and/or seeps into ground water. During transport, if the system is off, you could end up with readily contained debris given the containment system is designed to withstand external forces (think black boxes, but with nuclear material). Nasty still but much more controllable. I’d argue it’s on par with some of the nastier chemicals already routinely transported.
Another benefit of smaller scalable units would be the ability to readily transport aging units back to a central factory that routinely handles old units before major structural degradation occurs. One issue at Fukushima (and a majority of other nuclear reactors) is that the size and scale of each one is enormous requiring a lot of one-off resources to clean up, and so the incentives are to run them far past designed lifetimes and safety recommendations. Nuclear fission is very detrimental to materials, even in modern failsafe designs. But having an organization which routinely “recycles” units long before failure could allow both economic efficiencies, better safety due to constant practice, and dealing with smaller units which could be largely handled with industrial robotic systems.
The issue I’d worry about with such units would be security. Smaller units could mean potentially less security which would make for easier targets for motivated terrorists or rebels.