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Fruit juice and soda are effectively the same to your body. They’re both high-fructose liquids which spike blood sugar and lead to insulin resistance. The only meaningful difference is that a fruit juice probably also includes some vitamins that the soda doesn’t.

Sources: anything published by Dr. Robert Lustig @ UCSF

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Most fruit juices have a GI of ~50, which is moderate (about the same as a sweet potato). They don't really spike blood-sugar. Fructose is low-GI. They also contain other phytonutrients and flavenoids which may aid health in appropriate doses (e.g. hesperetin and naringenin in citrus juices).

And GI is linked to morbidity endpoints how?

Fructose interferes with satiety, mediated by leptin, ghrelin, etc.

This is well-documented in the literature. High-fructose, low-fiber diets make people overeat.

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