I hate to say it, but you're essentially saying "we can't afford to support people who are disabled, cannot afford the newest hardware, or are simply driving through a place with poor reception".
You have to do that cost-benefit analysis based on how important those things are to your business—for instance, screen reader support is an absolute necessity for the public sector and certain information-heavy apps, but probably not as important for visual tools.
I was talking to someone once about how ridiculously bloated Imgur is and that I had to use Imgoat because of the slow internet I was experiencing then. Of course they were trying to make all kinds of excuses like imgur not having servers nearby etc. But of course the really simple fact couldn't get to their heads that Imgur downloads like what 2-3 MB maybe even more of crap minus the actual image whereas Imgoat is something like 500 KB. No amount of network optimizations and caches etc are going to get over this fact. And also, such optimizations are over and above the page download size improvements anyways. If Imgoat used such techniques it'd be even faster. Most importantly: both sites have the exact same and simple core function, yet one site is so many times more bloated than the other. I will let you derive your own conclusions as to what this means.
And imgur also has the typical horrendous js misuses such as scrollbar hijacking that makes absolutely no sense etc.