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My first attempt was using the Blender API, you can take a look at https://github.com/akloster/blender-vraag

Currently I am trying to reimplement the "construct" part with Pymesh and Shapely, but I haven't published it yet.

Have you tried python-occ? http://www.pythonocc.org/

Thank you for the suggestion. I hadn't seen that yet. From a cursory look it's not completely what I am looking for, but maybe it can be useful.

One of the problems for me is that I am sort of stumbling into this "CAD" thing from a coding perspective. CAD programs like Fusion 360° or FreeCAD seem a bit too complicated for me, and through my grappling with the concepts I am reinventing some concepts/tools.

Particularly I want to develop 3D printed objects the same way I would do data science: Start with Jupyter notebooks, iterate, maybe end up with parametric Python scripts.

python-occ may be particularly well suited. They have ipywidgets to look at the models. https://www.youtube.com/watch?v=ieX_GC1sdrQ https://github.com/tpaviot/pythonocc-core/blob/master/src/Di...

Have you tried Cadquery for FreeCAD? Allows you to build your models in Python

There was quite a lot of openscad replacement going on in 2011. I even made a lua based alternative.