At my work, we've recently finished rewriting a macroeconomic model from Excel/VBA into Python. Would've been nice--and easier for the economists--if Python had simply been available in Excel. But I think the long-term advantages of teaching the econ modeling team Python plus gitand an agile-ish workflow (versus no defined structure that led to a tangled mess of VBA in the first place) will be worth it.

MS seems to push Python these days, but I doubt it will happen for Excel: they rewrote a lot of it in JS, so it makes more sense for them to provide a JS binding. Besides, making Python decently works on the Web version of Office would be a huge challenge.

Exciting, but that was over a year ago with no news on it since :(