I had a good performance boost using Photoshop and Maya. But if you're using a portable MacBook Pro that you're connecting every day, I wouldn't recommend it. The connect/disconnect experience is really flaky, and you'll probably spend a few times a week trying to figure out why the eGPU isn't connecting/disconnecting.
I switched to a Mac Mini at work (stock GPU build of course) with the same enclosure and graphics card, and the experience has been pretty delightful. If you're doing visual stuff, it's the budget version of a Mac Pro. It seemed to improve overall OSX responsiveness too, but perhaps that's just the new Mac Mini in action.
I still use the old MacBook Pro at home, but it's not my daily machine. Now I don't have to carry a bag to work, and my home laptop can cover things in a pinch. Using a desktop machine at the office for work has improved my work-life balance, and my productivity.