Seems obvious without thought to me that it’s mostly moot. Very few people will be running machines like we have for the last 30-40 years, most will be on Android/iOS where ad blocking will be minimal.
Savvy users will continue to block on machines that aren’t walled gardens and through pi-hole style blocking.
I think the cat and mouse aspect will be completely overshadowed by tech giants continually neutering their users ability to block ads.