Source: from the Midwest in a very rural area. Someone moved in right next to my parents. They aren't happy, but nothing they could do about it (while remaining a responsible human, a productive member of society, and not a worthless mooch) - they didn't have the money to buy the lot, so it is what it is.
Before people start talking about strip clubs next to schools or factories dumping waste into the aquifers. These neighbors are well within their by-right zoning regulations. They just have a house, and they just happened to buy the lot right next to my parents'. In California, it would have been perfectly acceptable for my parents to tie that development up for 20+ years with all sorts of ridiculousness. But in by-right zoning states, you just get housing built and move on because that's how the real world works.