I'm having the requirement to work with Node and Python now. I write my webapps in node but have data analytics scripts written in python to be invoked. I'm planning to use [python-shell - npm](https://www.npmjs.com/package/python-shell)
I remember coming across GraalVM. However, as I solo developer, I have found learning another new thing to be detrimental to my ability to getting things done. I have wasted way too many hours learning new frameworks, languages, platforms, etc.
I'm doing my best to avoid learning something new except when a strong compatibility with my current stack exists and is quickly implementable.
Generally if you want python/java interaction, we maintain a tool called javacpp that handles this, we even bundle cpython: https://github.com/bytedeco/javacpp-presets
GraalVM itself also depends on javacpp for a portion of its features (LLVM wrapper): https://github.com/oracle/graal/blob/315f5dcf69c2e73fd13a5f8...
I'd be happy to answer questions about the overlap of the 2. I can say I happily execute python scripts from our embedded python and even point the python execution at an anaconda distribution.
I don't recall now why I chose it over the much more popular python-shell. Sigh - the exploratory-spike log is sparse, and then "that all works, so why revisit low-commitment choices". I used it last year for a python helper, to offload some opencv and tensorflow optical tracking from electron.
(Both exist, and work, in javascript. But opencv had painfully subtle issues even with py3 vs py2, so I payed complexity to be closer to then mainstream center py2. And then moved tf over to work around chromium's excellent video latency and load (for passthrough AR) becoming much less so when also touched by the cpu.)