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I worked at a medical imaging company in Toronto in the 80's and 90's. Therac-25 was very much top of mind for all companies in our industry and changed everything from how we did Design, Development and QA to how the FDA reviewed and approved devices running our software.

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It was one of the standard examples in my introductory computer science classes, along with the Ariane overflow and the inaccurate system clock on some missile defence system that got a bunch of soldiers killed in Iraq when someone missed the scheduled restart hack.

The missile defense system issue:

https://en.wikipedia.org/wiki/MIM-104_Patriot#Failure_at_Dha...

> The Patriot missile battery at Dhahran had been in operation for 100 hours, by which time the system's internal clock had drifted by one-third of a second. Due to the missile's speed this was equivalent to a miss distance of 600 meters.

Brief summary of the Patriot missile failure in Saudia Arabia in 1991: http://www-users.math.umn.edu/~arnold//disasters/patriot.htm...

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