Since no one else has said it, find out which alums from your university are in Philly and set up informational interviews with ones in fields/jobs you find interesting. Everyone loves to talk about what they do/how they got to where they are. Key: follow up with a hand-written thank-you note. This is far more memorable than an email! (and do this for everyone who takes time to talk to you)
I would also set up an informational interview with these Philly folks to get a better idea of the local scene: http://www.dreamitventures.com/ I totally get that you want a job-job, but they will "get" your background and may even put you in touch with one of their companies and/or introduce you to others in the Philly tech community.
I'd also check out http://asktheheadhunter.com/ for advice on how to treat your job search the way a recruiter operates in matching companies and talent (essentially, you research the heck out of a place where you'd want to work and then show them how they need you). The "Ask the Headhunter" book is a bit repetitive but may be worth picking up as well.
Best of luck! And don't be too hard on yourself. The process will most likely have its setbacks.