For example, in Canada, I'm always a bit hesitant when I land on a .com website (is it USD or CAD?), but a .ca domain tells me I'm at the right place. Especially for multi-national companies like Amazon or The Home Depot.
I wouldn't use .us in the USA though—it doesn't seem to be very common, putting it in the same boat as .biz and all the other new ones. .com seems to be the de facto "US" TLD.