A) Want to use unsigned addons to play around, or tweak your existing ones[1]? Nope, even if you allow them in about:config, you can't; you have to use a special development version and update it separately.
B) Want to customize your keyboard shortcuts? Sorry, that's not safe, you have to use a crippled API that won't take effect until a given page loads.
C) Want to control your setup? Sorry, their "studies" feature is owned by the marketing team and can make arbitrary changes to the app on the fly, all the way up to its cryptographic infrastructure! (As we learned in the recent add-on mishap [2].)
I use Firefox, but they're not obviously better on these matters.
[1] Like, I don't know, if you made a big deal about underprivileged groups getting into coding, and actually wanted to take the concept seriously rather than just get some photogenic token to write hello-world for a photo op.