I broadly agree with your point but careful when saying “no obvious phenotype”. As my former boss likes to say about work in C. elegans: “Worms can’t talk. They seem healthy but maybe they’re extremely unhappy.” Less flippantly, we know that biological systems in general have huge plasticity to buffer environmental changes. The environment is controlled under lab conditions, so loss of robustness due to genetic changes will almost never be detected. We have no good estimate — not even a ballpark! — of how many of these 95 “no obvious phenotype” cases actually have no phenotype, and beliefs widely vary.