Grew up in Alberta, but spent a lot of time as a kid in the Kootenays in British Columbia, so no stranger to grizzlies. I've seen a few while hiking as well, very scary.
I think the idea that a handgun cannot penetrate a Grizzly's skull is a myth anyways. Plenty of accounts of people shooting attacking grizzlies dead with a large calibre handgun. Bear-spray can work but what if it doesn't or what if there's wind working against you?