It would be wholly dependent on the load and the technical implementation.
In my view the monitor would be a driver with standard knowledge and experience who could drive if the autonomous system encountered an edge case or for last-mile, i.e., from the freeway to the shipping or receiving facility.
Under those circumstances a load traveling ten hours with six hours of loading and unloading time would require two hours of active work and fourteen hours of standby.
Any driver would accept a lower rate for this kind of arrangement.