This is true. Not only is it impossible to prove anything in science and therefore reality, but we also view things through a blurry lens. Results arrive with a limited amount of significant figures or in the form of a statistic. Technically, although things cannot be proven in science, things can actually be disproven in science, but due to the blurry lens we are unable to fully do so. Instead science is largely about establishing correlations and to an even harder extent trying to give a blurry statistic to causation.
Do note that for math, you can prove things but two things must be assumed. The first assumption is that all axioms related to the proof are true. The second assumption you make is that logic as we know it is true and always consistent regardless of context.
There is one more interesting thing regarding science. Because nothing can be proven in science and because all science is, is establishing correlations, one thing that we assume is true in the real world is probability. In math the axioms of probability are basically arbitrary ratios assigned to sets with the theorems blossoming outward from different compositions of these sets and ratios. The theory itself has nothing to do with random events. So literally the theory of probability is just about sets and an associated rational number representing a portion of that set.
If we had a 6 sided dice and we rolled it billions of times the reason why the number 5 appears close to a 1/6 portion of all the results is a mystery. We literally assume this is the case and that the axioms of probability which are essentially just sets and ratios actually applies to random events and happenings. All other science is derived from this assumption.