If only more people would use org-babel...

If you're on emacs and like Jupyter, there's https://github.com/dzop/emacs-jupyter , which is pretty nice. I've been using it for a few days with Julia, and it works really nice. It also allows you to use different kernels from the same org-mode file, though I haven't tried to pass data between them yet (should be possible, though, at least it works in plain org-mode).