Ask HN: How do we “cure” cancer?

I’m a graduate student study Computational biology, and I understand cancer is a catch all term for a variety of diseases that occur in different tissues as the result of different oncogene interactions and other mechanisms. I’m really trying to understand whether how researchers and clinicians tackle specific cancers, and what a cure would or could even look like. Do we tackle some upstream system that prevents mechanisms that result in the slew of potentially cancerous outcomes for a given cell type? Are there common bottlenecks to tackle?