Yes, I'm saying this only because last 1.5 years I'm doing my kriya practice which includes meditation, breathing technic and few other things and it has been working wonderfully - since I "got it" I never had a single bad day. I am comparing this to having occasional bursts of depression, loneliness, self-doubt for a few years before.

I did not try strong psychedelics but the problem with them as with any kind of drug is the effect wears off inevitably. If you feel great for some time, going back becomes even more terrible than staying there, because now you know there are better states. What sets meditation apart is that it is a process which (at a certain level) lasts through the day and even becomes permanent. This is something you can not get with outside help because you will just become dependent on the source of that help.