Other sports have limits for molecules like EPO, where the limit is also different between men and women: https://www.nature.com/news/2006/060224/full/news060220-18.h...
This is just different because it is about the male hormone, and now the IAAF conveniently has a metric to distinguish between men and women.
It is just case that has no easy answer. Athletic games has been held for ages, celebrating the best people in their disciplines, while at the same time discouraging people to cheat.
It turns out some people exist with natural advantages, and this advantage is just particularly controversial because it is related to gender.
For those interested there is a 50 min bbc documentary about Caster called "Too Fast to Be a Woman": https://www.youtube.com/watch?v=f-UX0LE_tCg