I think Philip K. Dick's "Do Androids Dream of Electrical Sheep" (Bladerunner's inspirational material, yes; but very, very different) has an impressive walkthrough of these predicaments.
AFAIK Dick always wrote about "what is actually real?", and in this book, it's about empathy and wanting things to be real. He manages to incorporate several levels.
Animals, replicants, spouses and God. What about life-affirming replicants, what about deplorable humans? It is impressively thorough!
It's not an easy book to grasp (for me at least). My interpretations is that the "other's'" status is about our recognition through wanting other to want something and how difficult that is to accept and align.
If "the other" isn't going to want to recognize itself in your desires, the relationsship isn't real.
At that point, I think the subject has transcended robots.