Aerobic exercise is an effective treatment for depression
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Not so long ago I came across a twitter thread in which people shared very negative experiences with PE lessons in schools. My own experience was not as bad as some of theirs, but frustrating enough to make me hate the very idea of exercising. My body shape was average, but somehow I was very clumsy. Among boys, I was one of the the slowest runners, only faster than the few kids who are quite overweight. I was also extremely bad at sports. Could not dribble for more than a few steps, could barely hit a badminton bird reliably, etc.
My clumsiness itself was not something I felt bad about. It was the fact that my incompetence would be demonstrated in front of my classmates in a PE lesson that made me hate PE. In retrospect, they might not have noticed me anyway, and even if they did notice my failures, they are not going to remember. But this is not something a boy, eleven-year-old, driven by pride and a desire to show-off, could understand. What I learned from my PE lessons was simple: exercising sucks. Sport sucks. You better not do it if you've got the choice.
I have seen enough evidence to convince me of the benefits of exercising. I wish I could enjoy exercising more. But I just can't. I wonder how things could be different, if I somehow had the chance to enjoy my PE lessons more as a child.
Maybe it's whether it's enforced or by personal choice?
When I was running, I was putting in 8-10 miles a day. Cycling was around 1.5 hours for a weekday, 3-4 hours per day on a weekend.
I wouldn't say I was depressed at all in those times, but I was certainly stressed quite a bit and I did feel that the exercise was a cathartic escape from the stress and worrying. I'd kind of zone out at 25 mph, 30 miles from home on the bike and the mind would just clear.
I also loved the competition. I never won a race, but I placed second with a near win in a bike race. Racing on a bike is an experience of its own right. When you're in the peloton, it can be nearly deathly quiet. You can have a quiet conversation with the person next to you. All you hear is the tire noise on the road and the turn of chains over the gears. Zero wind noise. It's weird and magical. Something you don't expect or get to experience as an amateur training alone.
One particularly kind-hearted PE teacher had the (rather obvious) idea of sending the wheezies, fatties and wimps to the sports hall to play badminton and table tennis, while the rest of the class went off to the games field to play rugby. It was a revelation. I wasn't cold, I wasn't wet, nobody was trying to knock my teeth out, everyone else was equally bad - I was loath to admit it, but it was almost fun.
This was at secondary school (11 - 16). At my primary school (until age 11) we didn't have showers so the sports were more tame.
From age 11 on, also in the UK, we played rugby league, football (soccer), cricket, and hockey. Hockey was the only one that played some games boys vs girls. Mixed hockey seemed by far the most dangerous of the sports - for the boys!
Junior was cricket, footie and the inevitable rounders.
What kind of PE lessons do you think would have been suitable for your 11 year old self ?
Exercise is about self improvement, and at the start it does suck. It requires hard work and persistence along with pushing yourself outside your comfort zone.
Once you start improving and even getting good at something however it becomes enjoyable and you start to look forward to it.
If you don’t know how to get started I’d suggest picking something where if you had to, you could imagine yourself enjoying it, and getting a coach.
For me personally, I’ve found boxing to be a lot of fun, it burns the calories and teaches you useful skills.
With a good coach they should be able to help you progress at your own pace - all you have to do is show up.
Walking around outside is a pretty non-demanding and enjoyable form of exercise. It's particularly pleasant in a park, waterfront, or natural environment.
PE lessons as such never inspired me much, except for swimming lessons which seemed fun and useful. But in primary school we had this great thing called "recess" where we could just go outside and do whatever we wanted (or nothing at all) with whatever equipment they had. Staff were available for assistance if needed but didn't direct activities. Games and sports, if any, were generally self-organized.
I'm pretty sure that is a good general model for a school that would actually be fun and educational. Or at least a better balance of something like 10% directed activities vs. 90% undirected/self-directed.
Recess periods might be a good idea for day jobs as well.
Regarding sports, I think they're quite a bit easier as an adult when you have better coordination!
Rules and general movements were explained and shown to you once, and then you were left to your own devices only to be judged later on what you learned. (Learning by osmosis at that point, really.)
Several times it took one small comment from someone else years later and I was able to do the thing considerably better. (Which muscles to relax, for example, or wrong direction of a movement.) That should have been a teacher's job.
Poor motor skills seems to be associated with people on the autistic spectrum. I certainly fit into this mold, and I bet a lot of people here do.
My memories of PE are about team sports. Throw somebody with poor motor skills into team sports and they are going to have a bad time all around.
People with poor motor skills are not going to enjoy competitive sports. Competition might motivate some people, but if you always lose that's a pretty big demotivator.
Individual activities like running or weightlifting are probably a better match for a lot of kids. Something where your only goal is to be better than you started.
This study only looked at people who were recruited from inpatient or outpatient MH services; it excluded people who had other long term physical problems; and it found similar effects for solo or group exercise, and for exercise that used or didn't use equipment.
Anecdotally my life experience is that exercise is the best possible way to combat depression. The other day I was crushingly depressed and had been for a week. I went and hit my heavy bag for twenty minutes and came out feeling fine. The effect was profound and easily felt. I don't need a study to convince me further; my lived experience is a superior epistemic method here.
I'm much better now, and I think exercise was one of the key things that improved my general mood. It was a constant sturggle though for a while.
YMMV, of course, and I was never diagnosed or anything.
Of course, I was suffering from severe clinical depression not "feeling terrible for a week" level "depression."
That's really key, severe clinical depression profoundly affects your response to stimuli in pathological ways. Another example for me is severe clinical depression (of which I've suffered two episodes of in my life) makes me unable to taste food.
Good point. I'm interested in their answer on that.
> [...] and enjoy it?
Fuck me :) That was amusing!
No offence but you really don't get it. Exercise in that state we use as a coping mechanism. I guess he, like me, overdid it hence the vomiting (just a guess though - love to hear the answer).
There is no enjoying it because there's little if anything to enjoy if you're hurting inside. To repeat: exercise is a coping mechanism. It's not 'fun'.
Vomiting is simply my body's response to stress while disfunctioned by severe depression. During that timeframe, I was sitting in a room with coworkers discussing specifics of a project and that was just so completely overwhelming to me that I had to run out of the room and go vomit. Later that week I had to take an extended leave of absence from work because I could just no longer function at work.
I'm wasn't "doing it wrong," its severe depression that causes such a reaction, not intensity. My workouts are never particularly intense anyways. That's depression - it causes profound disruptions in response to stimuli. Other innocuous things make me vomit too when severely depressed as well. It's called severe clinical depression. I mean, that's literally a diagnosis criteria, anhedonia - An inability to experience pleasure from activities usually found enjoyable.
I can exercise just fine when not depressed without vomiting or feeling like garbage.
> Did you try backing off the intensity to a level where you could simply cope and enjoy it?
This is the equivalent of suggesting to a depressed person that they should just try being happy.
Given that context it's important that we don't force people to do anything unless we know it works, and the previous evidence didn't tell us that.
I'm glad exercise works for you, and I always support people finding out what works for them.
> Trump believed the human body was like a battery, with a finite amount of energy, which exercise only depleted. So he didn't work out.
Could you please delete all my comments from the site?
There is joy in moving (and good feelings afterwards) too, but if you are unable to feel that, then only the boredom and pain remains.
I did, however, find a medicine that worked wonders. Since then, I have worked out 30-45 minutes 5 days a week, but I certainly don't notice a difference in mood from before and after i started working out again.
Edit: I want to make clear that this is not a rebuttal of what worked for you, but a point to consider when discussing with others who may be suffering. If you speak in absolutes about what works, and they find that it does not work for them, they may end up feeling even more hopeless.
> The other day I was crushingly depressed and had been for a week
In my regrettably extensive experience, if you feel bad for a week then you can count yourself very, very lucky. I can't see what you describe as being depression, although of course people are very different (had GFs who had it bad for a week or so at a time every month).
> I [...] hit my heavy bag for twenty minutes and came out feeling fine
Depression made me exercise compulsively, to the point of damaging myself. It never made me feel better so I don't know why I did it, but I had to, and I understand this is common. Twenty minutes of exercise and you felt better? It's impossible to equate that in any sense with what I had.
There's a big difference between feeling really crappy and knowing you'd literally be better of dead, and being in that state for years continuously. That kind of things hurts inside, worse than physical pain (I know both).
> my lived experience is a superior epistemic method here
Hmm. Good for you.
High-intensity exercise, seems plausible. Aerobic exercise is an annoying timesink by comparison, even though it does nevertheless play an important role in building up cardio endurance.
I'll go a little further. Past few years have been extremely hard for me, haven't been able to concentrate for ~6 months to the point of not mentally being able to work (had to sign off sick (am in the UK)) and just starting to get back to work next week 1 day a week, unpaid.
I can just about keep my clothes clean, and mostly keep my flat clean. I'm mentally very unwell to the point of being unable to go to the pub and socialise as I used to. I was unwell to the point of being a danger to other people (am over that now, thank god. Yes, I did talk to the doc). I am coping, barely. I have no current interest in life, music, little interest in other people etc. I'm abusing drugs and alcohol as a way of coping, though in the long term I know that's a bad idea (and I draw a clear distinction between drug use/drug abuse, entirely independent from what's legal/illegal).
Point is, I feel justifiably terrible but I'm not clinically depressed. For sure I'm down, but I'm nowhere near the utter destructive blackness that is real depression, and I'm bloody grateful for it.
So I can't see what you describe as depression in any way that I can comprehend.
(NB, life sucks but any sympathy you can shove up your arse. I'd much prefer you took the piss, at least in a nice way. At least I'd get a laugh out of it).
Now I can cope, more or less, and don't mind living (though I'm not fond of it much). Full-on depression is where death is outright appealing. Full-on depression hurts inside, really hurts. I've described it as soul-cancer. It fucking hurts. It's difficult to explain how much it hurts. It's over now, but if that came back I doubt I'd be alive for more than a few months if that.
That experience, which was a huge chunk of my life, allows me to put this in perspective - things are shite now (in fact they're worse than I've described) but it could be so much worse. I can cope.
In other words it was not just one bad week, I was fucking depressed. It was one bad week after months of being down. But thanks for making me play "more depressed than thou", I hope I won this round.
I agree completely and totally.
I find exercise reduces stress, and that helps one cope with the day to day setbacks. If you are depressed, this should help.
Of course this doesn't apply to all depression, but I can give this anecdotally an HN comment, unsourced.
Higher physical activity in the general population is likely to have a significant preventative effect on depression, because chronic physical illness is one of the most significant risk factors for developing a depressive illness and exercise has a strong preventative effect on chronic physical illness.
Interestingly, it's also pushed on those with CFS, despite evidence that it actually causes harm. IIRC, there is a NICE review going on at present, but recommendations are going to be made for a while yet. Sometimes the speed at which the NHS works is literally painful!
This has happened to me on multiple occasions.
Just getting out for 30-40 every day minutes and sleeping and eating well does wonders for me. I get energized and life becomes full of opportunities, I see the bright side of people...
I am almost certain that is the circulation of the lymphatic system. For people working in front of a computer for hours a day it is very important.
Spain(most of it) is sunny most of the year and it is rare when I could not exercise outside, but in central Europe I notice it a lot with the dark winter.
This is something well proven, that over certain temperature, mathematical work drops enormously.
Having experienced that I have the hypothesis that the body regulates the temperature of the brain and if it is too high it will make it to slow down, just like a computer does and make you lazy so you do not generate more heat.
In the same way, it makes sense that if your lymphatic circulation is blocked, as it works only with movement, it will make you lazy so your cells do not generate more waste that can not be cleaned.
Not feeling depressed is good for a while until it starts to feel like you're not fixing the real issue. Tackling all those routine tasks like exercise, sleep, diet is really easy compared to doing the things that are really important to you where there is much more uncertainty, risk, and discomfort that cause me to feel very anxious which is very discouraging.
Doing things like exercise to help with depression is like trying to repair a cracked stone wall by painting over it so you can't see the crack anymore.
This is great. I think self-discipline is the underlying thread among all these items. When we have self-discipline and eat well, sleep right, and exercise it starts to spill over into work and personal relationships. And yes, it is a type of success begets success situation.
The point is, I will always have some problems, but with exercising for 2 hours, they will become to surface where I can emotionally access them.
Jogging works too, but I find Beat Saber is more fun and I have much easier time keeping a regular schedule.
It's a mistake to assume that people who don't currently exercise are doing this.
Anecdotally, when I'm exercising all the crap in my life just fades away to where just putting one foot in front of the other is all that matters. It's not a state of not caring, it's more that it doesn't exist in my head the same way The Game doesn't. It's Zen almost - calming and peaceful.
Less anecdotally, you can rationalize the release of endorphins as an evolutionary trick to get us to do something that while unpleasant used to be very necessary for survival. (Imo, whether this is true or not is not important. Rather it is a rational for productive self-delusion).
The motivation to start is often the hardest part for me, but I never regret it once I get going. In a sense, I always want to run soon but I never want to run now.
I have written less than a page of code (last sem in uni) but have the IDEE open in front of me 24/7. Stopped working out, stopped developing my hobbies. For context, I used to be a proper high functioning extrovert and juggled full grad level course-load with good grades through 2017 and 2018. have even landed my dream job starting in July.
It is frustrating to see people tell me to just get on with it. I am fully motivated to do the tasks that are piling on, but the absolute sense of mental inertia is something no one understands. I have blocked websites. Avoided "time wasting events" and stayed up at night hoping to do something. But, it has failed literally every time.
I am slowly inching towards a solution, and it has to do with making the task more mentally accessible.
Instead of working out at the gym, I do pullups on my door frame every-time I stand up from my laptop. I try to walk to the campus whenever needed instead of taking public transport to catch some sun and get some exercise. Instead of going to the gym, I follow the feet of my friend who is also going to the gym, just so I reach there first. (not even lying)
Making the task a series of small and achievable smaller tasks seems to have been the best approach so far. It's not perfect, but I am getting there.
I am however, sure about what my 'depression' (not diagnosed, so can't be too sure) is based in. My friends have all graduated and I have no peer group left. My relationship with my project guide is purely professional, and I feel like an imposter to ask him questions about simple things when I get stuck. Lastly, I am stuck in the project in a spot where the problem can't be broken down into a series of small steps.
I have seen plenty of others stuck in such a situation during their time in grad school. In almost all cases, external support is what works best. A new group of friends you can rely on. A gym buddy who will pull you to the gym. A mentor who is willing to go beyond call of duty to walk you through the block.
At this point, I can't wait to graduate and move to the new town, where I have established friends and get a breath of fresh air. Hopefully, that change will be sufficient.
If it is any consolation, things aren't as bad as I make it out to be. My life is technically speaking (from 3rd person POV) the best it has ever been. I have landed my dream job with a really amazing team. I have group of really supportive friends in the city where my job is. I stay far-away from family, but my brother is literally the best emotional support anyone could ever wish for.
This Monday, I will at least try and give one of our university counselors a visit, while I still have free university care. I have tried twice and bailed on it. Maybe 3rd time's the charm.
Lastly, sorry for venting out on the platform here. It's not your baggage.
The brain certainly works in mysterious ways. It is like fighting with yourself.
I do think this advice on its own is mostly /r/wowthanksimcured because the advice people really need is the how of setting up a situation where they will actually get out if bed and get started. And I don’t have an answer for that because I think I did it the hard way and kinda got lucky.
- Exercise at a set time every day. I find that morning is easiest for me due to a few tricks. But do what works for you. Also, if it's not working, then try something else.
- Designate some cloths as "exercise" clothes (whatever exercise you decide to do). At first, it literally doesn't matter what they are. Don't go out and buy something. Just put aside some clothes that are only for exercise. Make a rule that when the set time comes to exercise that you put on your exercise clothes. If you don't feel like exercising, then at least put on the exercise clothes!
- Morning works well for me because I set out the exercise clothes the night before (which is easier because I'm not about to exercise). When I see the exercise clothes in the morning, before I wake up I put on the exercise clothes. Following random rules when I am groggy seems to be easier than when I can think up good excuses.
- Keep in mind that you will almost certainly not want to do it. Keep saying to yourself, "Well, at least do X". Don't think past X. If there is a good excuse why you can't do your exercise today, try to put it at the back of your mind and think only about "At least do X". At first, X is just "put on the exercise clothes". Even if you know you are not going to exercise, put on the clothes. It will only take 30 seconds.
- Do some warmup before your main exercise. Keep it light and easy. After you put on your exercise clothes, you might as well do the warmup. Otherwise it's a waste of time to put on the exercise clothes, right? The warmup should be relatively short -- up to 5 minutes. If I'm running, then walking for 2-3 minutes away from my house is perfect. Even if you know that you are not going to exercise, just do the warmup. It's easy. It's light. You won't get sweaty. It's less than 5 minutes. If your schedule is so tight that 5 minutes is going to make a difference, then you are going to burn yourself out anyway. Just take the 5 minutes and do a warmup. You owe it to yourself to just have that "me" time.
- If you really aren't up for it, feel free to go back home after that warmup. But even if you are ill, or hung over or busy, or whatever, put on the exercise clothes. Then just do the warmup -- it's only 2-3 minutes (max 5 minutes). However, as you are dressed and warmed up, you might as well do 1 minute of jogging (or cycling, or fast walking, or whatever). It's only 1 minute and if you are really feeling bad, you can always go home after that.
- It's important to always allow yourself that real choice. If you are really feeling bad, then go home. But are you really feeling bad? It's easy to lie to lie to yourself, but it's also easy to detect the lie. If you don't know if it is a lie, then just do the 1 minute, or whatever. It's not going to kill you. You'll find out if you really can't do it. But if you can't, then go home after that 1 minute.
- When doing aerobic exercise, breathing is really, really important. If walking or running, breathe in for 5 steps and then breathe out for 5 steps. If you have no trouble with that cadence, then speed up. When you start to have trouble, switch to 5 in, 4 out. Then 4 in 4 out. Keep working your way down to 3 in 3 out, or even 3 in 2 out. Then adjust your pace until you can maintain that.
- Getting that breathing going is actually kind of tricky. If you are walking, you may have to jog a bit to get your breath going. Then you may have to slow down to a walk to maintain that level. Or you may just have to adjust your pace, but it takes concentration.
- If you are not in good shape, it may take longer than your workout and so you won't experience it, but you body will slowly switch from burning more sugar to burning more fat. Fat is interesting in that it already binds some oxygen. Because of that, it requires less oxygen to "burn". Somewhere around when you start burning more fat than sugar, you will get your "second wind". If you are super fit, this will happen almost immediately, but if you are not it can take 20-30 minutes to get there. The first time you experience it, you will be surprised. You will go from suffering and having trouble gulping down the air to it being practically effortless to get enough oxygen.
- For the first 2 weeks, no matter what exercise you choose, it will probably feel bad. It will be hard to get your breath regulated. It will be hard to push yourself. Your body will feel bad. It will be hard to keep concentration. When it inevitably happens, just think to yourself, "Yep. That's it. That's exactly what should happen." Too many people think that aerobic exercise isn't for them because they never get past this phase and they expect to enjoy it at first. Enjoyment comes later, unfortunately. My experience has been that it usually is about 2 weeks later that you have a day where you think, "Wow. That was great. I can't wait to do it again tomorrow". Then a while later you will feel the same way again. Eventually, almost every day (unless you are ill) that's how you will feel. It will even get to the point that if you don't exercise you feel absolutely awful and you are pulling your hair out until you get get a run, or cycle or swim or whatever in.
- Your body will hurt at first. It's important to understand the difference between "good" hurt and "bad" hurt. You will get some sore muscles from doing exercise. You may think, "I'd better rest because my muscles are sore. I don't want to get an injury". However, with sore muscles (even if they are really sore), this is not necessary or desirable. After 2 weeks or so, you will never get sore again (assuming you keep doing the same kinds of exercise), no matter how much you do. However, if you get a sharp pain somewhere, then slow down, stop, and figure out why you have the pain. Take a rest and if it persists, go and see a sports medicine doctor. There are some common training injuries (illial tibial band syndrome, shin splints, etc, etc). Googling can help. Try to do a different kind of exercise until the injury heals. Don't push that kind of injury!
- Exercise 6 days a week. One day off a week is usually enough to prevent over training unless you are doing really intense stuff (which you won't be). Trying to do less is just an invitation to "I'll make up for it tomorrow". If you are training practically every single day, there are no days to be able to make up. If you miss a day, you miss a day. So, just put on the clothes. You can't afford to miss a day. Just do the warmup. If you at least do the warmup, then you might do the exercise. Just do 1 minute. If you do 1 minute, you might do the whole thing. By the time you have gone half the distance, you are committed because you have to go the other half to get home ;-) Every day is dramatically easier to maintain than every second day (the the point where if you choose to exercise every second day, I'm willing to bet that you won't continue with it long term).
- Start off with only doing exercise for about 10 minutes (so 30 seconds to get dressed, 5 minutes to warm up, 10 minutes to do your main exercise -- 15 minutes 30 seconds total ;-) ). Every week, extend that by 1 minute. Only 1 minute! After 5 months you will be exercising 30 minutes 6 days a week (3 hours of exercise a week). From there you'll be in a good position to figure out what works best for you. The 1 minute of extra per week will avoid injuries. Injuries are crap because if you get one, you have to rest and then start the whole process over again.
- Realise that it is hard to do this. Take pride when you succeed. Forgive yourself when you do not. But the most important thing to remember: Today is the best day to start over. If you lapse, start over today. Just keep starting over until it sticks. It's totally normal to lapse. It's totally normal to start over. It's totally awesome when you string 2 days in a row.
Here's one park run that's coordinating with their local NHS Mental Health service provider around suicide prevention: https://www.sussexpartnership.nhs.uk/our-events/parkrun
But your point is one of the things that I found so irritating about the exercise advice. People would describe profound deep depression, and someone in the comments would say "go for a jog" (or "cut out sugar"), which always felt really trivialising.
Diet and Gut flora are incredibly important for mental health and overall well being.
In most 1st world countries, people eat way too much and often, unfortunately a lot of their food choices are heavily processed and cause massive inflammation.
Probably because it's so cliche that memes are made about it:
https://www.reddit.com/r/starterpacks/comments/6w783j/i_dont...
And this was also further complicated by the fact that lime juice can lose its nutritional character in some situations (such as certain sorts of storage), and so some experiments in using lime juice as a cure/prophylactic failed. It was also complicated because there's also high quantities of vitamin C in various fresh meats, and so crews that had access to these meats, but consumed minimal citrus, would also never seem to be affected. Tricky to nail down!
As a fun factoid, vitamin c is ascorbic acid, but it wasn't always called that. It was originally named hexuronic acid. It was renamed ascorbic (against scurvy) acid once it was confirmed that it was indeed absolutely what was treating and preventing scurvy. Another fun one is that this is also related to the slang term for a Brit - a 'limey'. The nickname came from the fact that the British navy was one of the first to start dosing their sailors with lemon/lime juice to ward off scurvy.
So the point of this is that if a whole bunch of people are suggesting something works, to the point of it becoming a meme, there may actually be something to it - even if it can be difficult to isolate the exact reason why, or why it may not work in 100% of cases. Definitively solving the mystery of scurvy took about 3,500 years from the point of it being formalized. So a bit of patience is probably justified for these sort of things.
As literally every single source you might find will affirm this, I'm at a loss for what to cite. Here [1] is a source that seems well written and informative, including some of the countless first person accounts as well. You can also look up the voyages of any famous trader/explorer/voyager you might be aware of. For instance Vasco de Gama, Magellan, Columbus, etc - you'll find horrid tales of rampant scurvy when you actually look into their voyages.
[1] - https://www.sciencehistory.org/distillations/magazine/the-ag...
Because he's making glib claims about a very important topic that aren't supported by the evidence. The only studies I could find on keto and depression were conducted on rats; I couldn't find anything on the paleo diet and I'm not even sure we agree on a definition of what paleo is. Veganism may actually make matters worse, because there's a real risk of developing a vitamin D or B12 deficiency if you aren't careful.
The evidence linking diet and depression is really very limited. Serious malnutrition can cause depression, a sensible balanced diet won't do you any harm, but any other statement about depression and diet has little or no basis in fact.
I’d say the opposite is true there are many available studies on dietary inflammation (ie chronic inflammation) and depression being linked.
See the inflammatory hypothesis of depression, also interesting is data is beginning to reveal a link between inflammation and the 1/3 of patients who do not respond to antidepressant medications. Generally when working antidepressants have an anti inflammatory effects.
It should also be noted that the diets mentioned Keto/carnivore/vegan all generally emphasize the removal of inflammatory foods (ie refined sugars, refined carbs, fried foods, artificial trans fats, etc...).
We still don't have any real idea of the causal directionality between inflammation and depression. The best available evidence (and the best available evidence is very weak) suggests that depression causes inflammation rather than vice-versa; depressive illness predicts levels of inflammation markers, but inflammation markers do not predict depression.
Some antidepressant drugs do have anti-inflammatory properties, but the reverse is not necessarily true. Several clinical trials of anti-inflammatory drugs have failed to show efficacy in the treatment of depression.
Presently, the inflammatory hypothesis is distinctly hypothetical; while some basic neurobiological research in mice support it, we have no real clinical evidence to suggest that reducing inflammation has any meaningful effect on depressive illnesses.
https://www.sciencedirect.com/science/article/pii/S088915910...
https://www.biologicalpsychiatryjournal.com/article/S0006-32...
But no matter how precise and intentional a diet, I don't think it can ever provide the euphoria that aerobic exercise provides.
For example most antidepressants are at best getting people a few points (from what I’ve read).
It isn't really my hypothesis. It's what metacognitive therapy suggests. It's a therapy developed by a psychologist that worked with CBT before suggesting some changes to the treatment. http://mct-institute.co.uk/depression/