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Do you have to remove a gene from every cell in the body, rather than modify the blood cells so they don’t attack the rest?

Right--see the paper I linked to above for an example of that. Here's a summary article: https://www.cell.com/molecular-therapy-family/molecular-ther...

If you can't access it then shoot me an email at ron gejman at gmail dot com and I'll send you the pdf.