Optane will be seen as a really big main memory by the OS and that's it. So, I don't get why there will be severe changes in software..
Take a look at how cagey Intel is acting about Optane: https://www.semiaccurate.com/2018/05/31/intel-dodges-every-q...
This is the same behaviour as with Intel's LTE chips, where promised features keep slipping (much to Apple's dismay).
https://www.storagereview.com/intel_optane_dc_persistent_mem...
All of which looks to solve the wear problem even if it means higher price and latency.