Maybe try a linear isomorphic layout, Janko style (see my top level comment; I'm coming from piano).
Edit: Is that any four note square? Just squares, or rectangles too?
Edit: Is that any four note square? Just squares, or rectangles too?
from their webpage [1]:
> If 3 note pads are pressed that are 3 corners of a rectangle, presses to a note pad that is the 4th corner of that rectangle will be ignored.