My company (zeroK NanoTech) probably wouldn't exist if it where not for this program.
NSF SBIR can aid in the translation of technology that sits in the no-mans land between basic research and commercial technology. In my case the basic potential for our tech had been developed when I was a postdoc, but the federal lab where I worked (NIST) wasn’t going to be able to translate it. At the same time, there was not a great chance to obtain venture or similar funding because the market was a bit too small.
Building off the results of our SBIR-funded research we were able to obtain additional investment from a larger company interested in our technology.
The Phase I program is competitive, I recall about 15% of applications are accepted, but the application here isn’t so onerous, btu the funding amount isn’t very large; this is just for ‘proof of concept ‘ work. The odds of matriculating to Phase II and a much larger pot of money are better, about 40%. There is a decently long gap between your decision to apply and beginning of the project, but I know the NSF is working on this. The NSF is also unique in that you can apply with just about any kind of technology; most other SBIRs are not anything like this.
I’ve also served on review panels for these grants. While it is the case that some applications come from largish companies who seems to subsist on SBIRs, the NSF makes a big effort to invest in 1st time applicants if they have a solid plan. My ‘company’ in our first application was just myself and my cofounder and very little other resources and we won our award. Once you are an awardee, I found the program officers to be very helpful.