The minimum connection latency is 800-1000 ms, and the maximum download speed is 1-3 Mbps. That's with a 10 GB bandwidth cap though, so my actual download speed is 10-100 kbps for 90% of the month.
Any live video/audio/screen sharing is not possible. I have to schedule transfers for large files (1-5 GB) overnight, which are not bandwidth constrained during early morning hours.
I can get away with it because all of my work communication is through text channels.
It's not for everyone, but it's possible. For me, getting out of the city and living in the mountains with nature is well worth the trade-off of giving up some modern conveniences.
In all fairness, it's not a great option. My dad is at the very end of a DSL line in Maine and Internet is pretty bad. Neighbors who are a bit further out use a combination of satellite and wireless hot spots (on marginal cellular) and no one is very happy.