I would consider a change from ingestion via IV to insufflation is a pretty major development and all around improvement on the existing drug and.method of administration. If someone managed to create an ingestable pill or nasal spray for insulin they'd win a Nobel prize. While the scale and importance of that discovery is greater, the fact that such a switch in delivery method is that significant leads me to believe this controversy surrounding a nasal spray is more outrage porn than actual reality.