For my first job, I ran through generic job sites for 3 months with no luck and a lot of frustrating idiotic questions (one person rejected it because she couldn't open PDF and another rejected me in a phone interview for not knowing the company's address by heart).
I eventually just ran through all my Facebook friends asking for a job, and got one with an old family friend. Another two friends referred to me other job opportunities which I later turned down. And I basically just went through 15 people.
Like @pradpk said, the quality of your resume and anything you apply with is key. Job search success is basically (Volume ) x (Conversion Rate).
Hop on Linkedin. Sort individual profiles by Titles/Market/Industry/Key Word, etc..
Ex: CTO , VP Engineering, Manager E-Commerce
Then reach out to them direct.