After having worked on JS for some large web apps that need good graphics performance, the two rules of thumb in my head for making JS fast are: 1- avoid dynamic memory allocation, and 2- avoid using the functional primitives like map.
The first one is more or less true in all languages, memory allocation always costs a lot, and if you can pre-allocate memory and/or re-use memory along the way, the code will run faster. This means paying attention to what things in JavaScript will allocate memory under the hood, use of dicts, use of 3rd party library and framework functions, etc.
The second one is a bummer; I love using the functional primitives. But map is slower than a for loop, all else being equal. It has gotten relatively faster over time. I mostly use functional everywhere, and only resort to for loops in performance critical code.