Absolutely... neighborhoods, towns, and roads surrounding former major industrial centers (or mining towns), and occasionally the city itself. By land area, a lot of the US is like this, you just have to do a lot of driving if you are on the coasts, or fly to a small airport and drive to a different small airport.

We've had ghost villages since colonial days ( where native americans chased out of their villages or wiped out ) before being repopulated with european settlers, ghost towns from countless boom and bust cycles ( fur, timber, oil, gold, etc and of course the great depression ) and most recently the rust belt which is still ongoing problem.

Not the US, but much of the countryside in Japan is undergoing similar demographic and economic collapse. Most visitors stick to areas accessible from airports, trunk roads and shinkansen lines, so it hasn't gotten so much international attention. But if you rent a car and drive into the mountainous interior, or outlying regions like Shikoku, you'll find plenty of emptying, aging villages, adbandoned stores and factories and return-to-the-state-of-nature decay. Richard Hendy's blog, Spike Japan, had many well-researched and beautifully written posts on this phenomenon, unfortunately he stopped updating a few years ago. https://spikejapan.wordpress.com/

Appalachia...

There are lots of places like this in the rural south and midwest. Seen plenty first hand.