Just a counterpoint. I have taken prescription hydrocodone, for occasional use, for over ten years. I have been careful not to develop a tolerance. (because I want it to work when I need it.) It improves my quality of life. It's just a tool. A useful tool, like JSON, and unlike XML. Use it when needed, and don't use it when not needed. There are times I would have gone home from work, but sometimes even 1/2 tablet can make a huge difference.
Maybe this is related and maybe not: I also do not drink alcohol and have never seen any reason why it would be appealing.