Opiates kill[1], and are used recreationally. Those are two big differences.
[1] SSRIs _can_, but rarely https://www.ncbi.nlm.nih.gov/pubmed/9786310
[1] SSRIs _can_, but rarely https://www.ncbi.nlm.nih.gov/pubmed/9786310
SSRI apparently has a withdrawal problem even with proper usage