Retdec is ... okay.
On small binaries it's usable. On even average sized windows binaries (a few meg), not really.
Like on things that IDA takes 10-15 minutes and a reasonable amount of memory (like a 7 meg windows binary), retdec can take forever and unlimited amounts of memory.
I started fixing a lot of the memory issues (completely recursive CFG traversal, etc), but there are also very serious algorithmic issues (N^3/N^4 algorithms in the optimizers).
If i disable a lot of the backend optimizers, i can make it work okay.
But then the output is also a lot larger/worse. To be fair: It used to be about 50x bigger than similar IDA output. The latest development version of retdec now has a new backend IR converter, and the output is only 5x-10x bigger than IDA output.
So as a TL;DR: retdec in its default state is unusable for anything but small binaries. If you understand what is going on, you can get it to work on a lot of binaries as long as you have a ton of memory and time to spare.