The beefiest you can. Exactly.
A 2U or 4U server is $10k to $20k. You're going to fit all you can in the box, including a minimum of 512GB of memory.
It's not just about license costs though, it's about hardware costs and capacity management. You want to have as few servers as possible for a given capacity, it's easier to manage and cheaper. You must have VmWare to abstract the hardware, a bit like AWS. You work with virtual machines and it packs them on the hosts.
Last I bought it but that was a few years ago. VmWare was $5000 per node for the full package. There was a free edition limited to about 100 GB of memory, but without cluster management and live transfer of running VM (vMotion).