Less flexibility in starting a company: You can't choose to bootstrap unless you do it as a side hustle at a megacorp, and it's hard to not compete with a megacorp because it does everything. You have to take VC funding and follow VC rules to some degree, and it may not be a direction you wish to follow. This is a feedback loop.
Oligopsony employment conditions: If you wish to build savings and not spend all your money on rent, you can really only work for the largest and best funded companies, and even then you need to negotiate at a disadvantage, since they have far more information on the employment markets (because they're big) and they each know the other big players (because they're few) and can bound salaries through price leadership. This is also a feedback loop.
I'm concerned we will see fewer "real" companies like Intel/Apple, and more Snapchat clones and e-scooter startups. Less meaningful bets, less drive, and more complacency -- borne out of the desire to cannibalize social trust (e.g. if you work hard, you earn shelter) and the societal fabric (e.g. all people deserve shelter as a basic human right) for privatized financial gain.