At a "couple of hundred microamps" penalty, this more or less kills a wide range of potential products, ie battery-operated products like smart sensors or remote controls and the like.
One of the most important factors for a long lifetime is to minimize the static power draw, and running at 0.1--10 uA is quite common.
A common CR2032 has about 225mAh. If you can get 80% out of it, you have about 225 * 1000 * 0,80 / 24 = 7500,0 uA-days. At 10uA, you have roughly 2 years (depending on usage etc). At "a couple hundred uA", you'll have two months.