I would say that the main feature of a Lisp Machine is that you do everything from within Lisp.
I don't know of any papers on the Symbolics hardware that are not behind the ACM paywall, how much did it really differ from the other Lisp Machines ?
Lisp is good as a language for humans, and it used to be used in hardware because that was necessary to run lisp code fast. That hasn't been the case for ages.
What modification or addition to the CPU (or wider computer architecture) would be most effective in making typical lisp programs run faster?
Hipsters?
Or does it need hardware parenthesis support too? ;)
http://pages.cs.wisc.edu/~markhill/papers/computer86_spur.pd...
The basic instructions (Table 3) are close enough to RISC-V but it also had a few Lisp specific instructions (Table 4). Though the name J Extension for RISC-V might lead you to think it is only about Java or Javascript, the group working on it is also interested in making it as good as possible for Lisp.