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I'm a long time pi-hole user and follow the subreddit and discourse regularly. You'll find many a pi-hole user with whitelists. The following are pretty common.

* https://discourse.pi-hole.net/t/commonly-whitelisted-domains...

* https://github.com/anudeepND/whitelist

I have ~2.2M domains blocked. There's just no way that I wouldn't have false positives in that big of a list.

1 million here - nothing whitelisted or knowingly broken.

Unfortunately some of the more extreme blacklists can block legitimate error-reporting software among others that I commonly use for work. Same goes if you work in analytics you'll have to open up some just to access your dashboard.

I work in the cryptocurrency space and a several legit sites and APIs are blocked in more than one list.