Recently there has been a lot of talk about the intermittent fasting diet (fast 16 hours, eat for 8). My friend is a doctor and started the diet himself a few months ago, and takes his bloodwork every week. He says it's making huge improvements in his cholesterol and other blood levels.
I've been trying myself recently and so far no big changes, although I have lost a couple of pounds. But I think that's just because I had to cut out late night snacking!