I've been told, but never actually looked it up, that there is a theorem that proves you always have to have at least one single point of failure.
I don't know if the following is actually true, or just a rumor, but I've heard that at least one aircraft whose mission called for very high reliability didn't have a comparison unit: the redundancy extended all the way to having the 3 independent flight control computers each control a separate actuator on each flight control surface. If one of the systems went bad and tried to move the surface incorrectly, the other two would physically overpower it.
That still has a single point of failure, but now that point is the control surface itself. If your control surface itself has failed it no longer matters if the 3 computers controlling it agree.