Even if it only replaced Windows LTSB/Embedded, I'd still prefer an ATM, checkout, or gas station terminal I was using was running on managed code. Doubly so for the next generation of Nuclear Powered submarines[3].
Plus between virtualisation and silo-ed software management ("Apps") it seems entirely plausible to move the PC/Laptop to the next generation.
[0] https://en.wikipedia.org/wiki/Midori_(operating_system)
[1] https://en.wikipedia.org/wiki/Singularity_(operating_system)
[3] https://mspoweruser.com/uks-nuclear-submarines-runs-windows-...