I'm not really so sure what makes this an iPhone specific "framework". Its just a safari browser with javascript, except you can only capture click events.
All you really need in order to make a website iPhone "friendly" is keep buttons > 40x40 px and use:
<meta name="viewport" content="width=320; initial-scale=1.0; maximum-scale=1.0; user-scalable=0;">
Beyond that, any other traditional web framework out there works just fine.