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Comment by systematical | Hacker News Reader

As someone whose done shrooms around 50x I don't think they should be illegal. But I also don't think you want the average Joe to have easy access either. Low doses of 1 gram or less are manageable by most but at high doses of around 3 or super high like 5 gram doses your connection to normal reality loosens.

When ever i consumed high doses I always marked the expected peak time and eta to near baseline so I could use that to calm myself if I became too high. I don't expect this approach from most people. And that worries me.

It's a amazingly calming feeling to be able to say to oneself "wow I am really fucking high only 1.5 hours to near baseline" while staring at a third eye on your best friends forhead.

I don't really use them any more as I am enjoying sobriety more and more as I get older.

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Is the disconnection to reality persistent after it’s out of your system?

I agree about average Joe access. I live in Colorado and a lot of people, “adults,” cannot even responsibly take marijuana edibles.

Speaking from personal experience, residual 'disconnection' / difficulties resolve after ~48 hours. I actually feel more connected to 'reality' during/after tripping, but everyone's experiences vary.

Lately there has been some promising research into psilocybin's long-term effects on the brain and specifically depression - it's becoming clear that the drug has a unique effect in breaking down old (potentially negative) pathways/connections and allowing new (potentially healthier) connections to form in their place. Really interesting stuff.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367557/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640601/

Do you have any experience with micro-dosing? I've personally never eaten less than a half gram and I think a micro-dose is about a tenth of a gram.

Have you read "how to change your mind"? It touches on the subject. There is also erowid.org that might have the information you're interested in.

Yes, although a good amount of academic research and most of my personal experience has been with LSD as opposed to mushrooms. Mainly due to the increased duration and slight stimulant properties.

Nothing but good things to say about the practice provided you keep dosage and frequency at the 'micro' threshold. My roommate and I ran a pseudo-blind study (50% chance we'd get LSD on a microdose day, 50% water) and both noticed increased energy, empathy, creativity, and general quality of life.

How to Change Your Mind as someone else suggested is a great place to start.

First disconnection to reality cannot be explained, only experienced. If you have not experienced hallucinogenics than attempting to comprehend that meaning is likely futile. Furthermore, each individual may have their own unique experience/definition of this disconnected reality. It makes conveying experiences very difficult.

I'd say 24 to 48 hours. Though at 8 hours post consumption you are pretty much back and I think most of what remains is system shock. LSD is an entirely different story as the trip can last twice as long as shrooms. Despite the effects being less physically severe (i.e. no stomach discomfort) I was never a fan. Twelve hours of being high is just too long for me. Would be nice to get thoughts from someone who has taken lots of LSD as my experience is limited to about 3 trips.

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