I use provigil when I'm on a work bender or playing poker. Helps a lot, no increase in anxiety, in fact I barely notice I've taken it except for the fact that concentration/focus is through the roof.

As most everyone knows, I'm a total stoner, so I won't get into that except to state that it's been nothing but positive on the quality of my work as well as quantity. But there is direct causality with the quality and variety of bud in question.

I don't drink alcohol, nor do I do any other drugs. Although I did a lion's share of ecstasy and LSD back in the early 90's.