When astrophysicists work on this activity, they use (no surprise) computer vision. The lab's software automated the process these nova hunters ran manually: we subtracted two images of every segment of the night sky taken on different dates to see if any new bright objects appeared in the difference. If so, it's possibly a supernovae!
Because there are so many stars out there you can use this method to predictably discover large numbers of supernovae when you need to study them. They called the project the Nearby Supernova Factory ( https://snfactory.lbl.gov/ ); as far as I know this is still the preferred method.