A report analyzed the entries to Nature one year and found that very, very few of the papers actually met Popper's criteria for falsifiable hypotheses, and in fact most of the papers started out with an exploratory aim and documented their findings. This means that to adopt the Popperian idea that only falsifiable claims are science means we must reject good science. One must also consider what opportunities are being missed if we were to force good science to adopt strictly falsifiable hypotheses before research commences - this would mean that every exploratory paper would need to be redefined (or rather, firstly defined) as a falsifiable hypothesis... in an attempt to please Popperians.
It is also a stretch to say that science must be empirical or carried out in a particular way to which falsifiability is congenial. There are good arguments that even philosophy[1] or mathematics can be considered sciences, and indeed they were (see Wissenschaft in Kant and Hegel for instance).
Furthermore, it's been argued that Popper's theory of falsification actually includes bad science (pseudoscience). From SEP[0]:
>Strictly speaking, his criterion excludes the possibility that there can be a pseudoscientific claim that is refutable. According to Larry Laudan (1983, 121), it “has the untoward consequence of countenancing as ‘scientific’ every crank claim which makes ascertainably false assertions”. Astrology, rightly taken by Popper as an unusually clear example of a pseudoscience, has in fact been tested and thoroughly refuted (Culver and Ianna 1988; Carlson 1985). Similarly, the major threats to the scientific status of psychoanalysis, another of his major targets, do not come from claims that it is untestable but from claims that it has been tested and failed the tests.
[0] https://plato.stanford.edu/entries/pseudo-science/#KarPop
[1] https://web.archive.org/web/20170621073301/http://www.philos...